PRP for thin Endometrium: Suitability, Success Rate, and More


Dealing with infertility can be emotionally exhausting, especially when faced with the challenge of thin endometrium. However, hope is on the horizon. PRP therapy has emerged as a potential miracle for women struggling with this condition. The idea that our body’s natural healing abilities can be harnessed to restore and regenerate the endometrium is just amazing. 

However, a lot of couples are not aware of it. In this blog, Apex Hospital – home to the best IVF experts and general surgeons in Sirsa – will explore how PRP for thin endometrium offers a safer path to pregnancy. 

Let’s start by understanding what exactly these terms mean:

What’s PRP Therapy?

PRP therapy involves extracting a small amount of your blood. Doctors then process it to concentrate the platelets. This platelet-rich plasma then gets reinjected into the target area. The platelets release a variety of growth factors that induce healing, tissue regeneration, and better core functions. 

While initially utilized in the orthopedic and sports medicine fields, PRP has become a standard in dermatology and fertility treatments.

What’s a thin Endometrium?

Talking about endometrium, well, it is the inner lining of the uterus that becomes thicker during the menstrual cycle. It ensures that the embryo gets implanted in the ovary. In some women, however, the endometrium may not be thick enough. This decreases the chance of implantation. As a result, the possibility of pregnancy also decreases. 

Gynecologists refer to this issue as thin endometrium or thin endometrial lining.

What Causes Thin Endometrium? 

There are many reasons associated with thin endometrium. Here are the most popular ones:

  • Hormonal imbalances
  • Uterine scarring or adhesions 
  • Infections
  • Age-related decline in reproductive health
  • Repeated miscarriages or failed fertility treatments

A thin endometrial thickness (typically under 7mm) can complicate efforts to conceive. Even with assisted reproductive technologies (ART) like In Vitro Fertilization (IVF)!

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How Does PRP Help with Thin Endometrium?

As we said before, PRP therapy gives brighter pregnancy prospects to women who have a narrow endometrial thickness. And the reason is its ability to repair tissues. PRP therapy uses the body’s innate healing processes to trigger cell growth and blood circulation improvements. 

The growth factors released by the platelets activate the cells in the endometrial lining. These growth factors cause the tissue to regenerate, making the endometrium thicker and more tolerant to embryo implantation. 

Consequently, PRP therapy produces better fertility results for women with insufficient uterine linings. Particularly in cases of recurrent implantation failure during assisted reproductive treatments like IVF.

Here’s a step-by-step breakdown of how the PRP process works for treating thin  endometrium:

Blood Draw: The process begins with a simple blood draw from the patient (usually about 10-20 milliliters). 

Platelet Concentration: The collected blood is then centrifuged to concentrate platelets. This process involves spinning the blood to separate out red and white blood cells. Thus, allowing platelet-rich plasma to be isolated. 

PRP Injection: After the PRP is prepared, it is injected directly into the uterus. Gynecologists make sure that it is done with precision so that they can target the endometrial lining; improving its thickness and function. The growth factors in the PRP stimulate the cells in the uterus, encouraging them to regenerate, increase blood circulation, and develop a healthier, thicker lining. This enhanced lining is critical for supporting embryo implantation and improving pregnancy success rates, particularly for women undergoing IVF or other fertility treatments.

The entire PRP procedure is minimally invasive and is usually completed in one office visit. Patients typically experience little to no discomfort. Also, recovery time is minimal. Meaning, women can continue with their fertility treatments soon after the procedure. 

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What are the Benefits of PRP for Thin Endometrium?

While PRP for thin endometrium is a relatively new application, early studies, and patient experiences suggest that it holds significant promise for improving endometrial thickness and fertility outcomes in women with a history of a thin uterine lining.

Here are some more benefits: 

  • Natural Therapy: As we mentioned before, PRP employs your own blood. This decreases the likelihood of facing allergic reactions and blood rejection by the body.
  • Minimally Invasive: The method is rather uncomplicated. Only a few blood draws and injections are needed.
  • Quick Recovery: Unlike other surgical methods, recovery after PRP therapy for thin endometrium is really thin. This makes it possible for the patient to go back to their normal routines within weeks after the treatment.
  • Complementary to IVF: PRP uses IVF treatments mainly to improve IVF success rates.

Success Rates of PRP for Thin Endometrium

PRP (Platelet-Rich Plasma) treatment is showing promise for women with thin endometrium, particularly those struggling with fertility. Here are the key findings:

Endometrial Thickness: PRP significantly increases the thickness of the uterine lining. In one study, it was found that thickness increased from 6.09 to 8.67 in the PRP group; compared to 6.15 to 8.04 in the control group.

Pregnancy Rates: Clinical pregnancy rates were higher with PRP—32.5% vs. 14% in controls.

Success Rates: PRP has shown a 44.12% pregnancy rate compared to 20% in controls, with better implantation and live birth rates.

Fast Results: PRP typically works within two or three menstrual cycles.

Even though it’s a new treatment, results discovered by gynecologists point to how encouraging PRP therapy can be for improving pregnancy outcomes in women with a thin endometrium.

PRP for thin Endometrium: Final Words 

PRP treatment of thin endometrium is one of the most exciting and promising therapeutic interventions for women with fertility challenges. But as with any other medical treatment, it is recommended to discuss your specific case with a gynecologist. They will tell you whether or not PRP is right for you.

At Apex Hospital, our team of highly experienced IVF and fertility experts is dedicated to providing comprehensive care for women with thin endometrium. Using our state-of-the-art facilities and the latest techniques, we can help you explore your options and achieve your family planning goals. 

So, what are you waiting for? Contact us today by calling on +91 91680 39000 or +91 82229-66666

Check out our recently published posts as well: 

Everything about laparoscopic myomectomy 

PCOS medical treatment and everything else 

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Also, check out the services we offer at Apex Hospital:

Best surgeons in Sirsa

Hysteroscopy and laparoscopy fellowship in India

Infertility IV training course in India

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