Low AMH levels can feel like hitting a brick wall for many women who are walking the path of becoming mothers. Anti-Mullerian Hormone is often seen as a measure of ovarian reserve. Their low levels in your body can make conceiving naturally a BIG challenge. And this is exactly where stem cell therapy enters the scene!
While there are many treatment options available, it also shows potential to rejuvenate fertility. More and more women, be it in India and across the globe, are turning to this cutting-edge solution as they search for hope beyond traditional methods. But that also raises some important questions like:
- What is stem cell therapy really?
- How does it help with low AMH?
- And where can you find it safely?
In this blog, Apex Hospital – a trusted IVF center in Sirsa – will answer questions related to stem cell therapy for low AMH. Our insights will pave the way for you to make informed decisions. Turning your journey to parenthood a little clearer and a lot more helpful.
Let’s start.
What Is Stem Cell Therapy?
An innovative medical approach, stem cell therapy utilizes remarkable, undifferentiated cells with potential to develop into various specialized types to aid in repair, regeneration, and replacement of damaged or diseases tissues or cells within the human body.
These stem cells can either be sourced from an individual’s own body or a donor. They are then utilized in clinical settings due to their unique ability to self-renew and transform into specific cell types like muscle, nerve, or blood cells. Overall, it’s a perfect treatment that conventional treatments may fall short of.
How Stem Cell Therapy Helps With Low AMH?
Dr. Manisha Mehta – renowned obstetrician and gynecologist at Apex Hospital, Sirsa – is personally leading cutting-edge research in this area. Recently, she explained that this type of therapy is not merely concerned with increasing the number of eggs but also with the quality of eggs, which determines the outcome of conception and pregnancy.
She emphasizes meticulous patient selection and treatment plans to ensure maximum benefits. The current clinical study by Dr. Mehta is through the application of mesenchymal stem cells derived from various sources. Exploring their regenerative properties in ovarian tissue. Her work focuses on learning more about how these cells can rejuvenate dormant follicles and enhance hormone production, leading to new fertility treatments.
There’s also this case study by PubMed Central which tells how 2 women with decreased ovarian reserve (low AMH) underwent autologous bone-marrow-derived stem cell transplantation. It was paired with platelet-rich plasma for ovarian rejuvenation. Result? Both had restored ovarian function and menstrual cycles. There was an increase in oocyte yield and embryo function.
Another trial was conducted on 15 women. All of them were having POI (premature ovarian insufficiency). Gynaecologists injected autologous stem cells into the ovary. It was observed that natural pregnancies occurred in 4 females within 3 months. Eventually, 7 achieved clinical pregnancies with 55 successful births.
Sure, their AMH and antral follicle count did not change significantly but embryo numbers improved. Indicating functional benefit. Next up, we have research conducted by IJRCOG. 50 women with low AMH enrolled in it. After repeated autologous stem cell therapy, they saw an upsurge in AMH and antral follicle count (AFC) and a decrease in FSH levels. The total pregnancy rate reached 4% after three cycles.
Inspired by these promising findings, renowned gynecologist in Sirsa, Dr. Manisha Mehta, is actively working on advancing this research at Apex Hospital. Although it has promise, she advises patients that stem cell treatment is still an emerging field. So, it should be approached with cautious optimism. She underscores the need to have an open line of communication regarding the possible risks and benefits.
Her research is designed to benefit both local and international female patients with low AMH levels. This positions Apex hospital as a leader in advanced reproductive therapies.
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What Goes Into Stem Cell Therapy For Low AMH Levels?
Although this procedure offers a promising solution for women with low AMH, how exactly it works is still a question for many. Here’s how exactly it should work:
Collection of stem cells: In order to reduce rejection risks, doctors take stem cells from the patient’s own bone marrow or adipose tissue.
Processing and preparation: Once collected, they process stem cells in a medical laboratory. Concentrating the population of regenerative cells that will later be used in therapy.
Targeted infusion: These prepared stem cells are then infused back to the ovaries through a minimally invasive procedure which is, in most cases, guided by ultrasound technology to ensure that the process is executed accurately.
Regeneration and differentiation: Once stem cells reach the ovarian environment, they gain the ability to self-renew and differentiate. They may become cells that help repair or rejuvenate ovarian tissue. Possibly reactivating dormant follicles and supporting the formation of new eggs.
Hormonal response: Clinical trials have shown that AMH and AFC rise conusively over time with subsequent treatment cycles being paired with a decreasing FSH. These alterations are associated with better ovarian reserve and fertility.
Cycle monitoring and support: Once the process is done, doctors will routinely check on your hormonal levels (AMH and FSH), number of follicles, and overall ovarian response in months. The goal here is to stay up to date on your progress and guide further steps.
Potential outcomes: Women with low AMH levels, premature ovarian insufficiency, or early menopause will be offered a renewed opportunity to conceive with their own eggs after successful stem cell therapy.
Who Can Consider Stem Cell Therapy So Far?
Whilst low AMH counts are the most prevalent sign that a female can seek stem cell therapy, there exist plenty of other conditions when the procedure can help. Top gynaecologists at Apex Hospital and around the world have discovered that women dealing with inadequate ovarian reserve, premature ovarian insufficiency, and early menopause (in which the ovarian activity is impaired beyond that of the stage of aging) can also be ideal candidates for stem cell therapy.
It can also be thought of when overt treatment forms of fertility like hormone treatment and IVF have had limited success. You can give a further boost of regeneration to ovarian tissue and eggs quality. Besides low AMH, stem cell therapy is suitable for women with uterine issues like thin endometrium and intrauterine adhesions where repairing and regeneration are needed to increase implantation potential.
Patients with unexplained fertility who have tried other treatment options will also find a new hope with therapy, given that it can restore cellular health to the ovaries. Moreover, stem cell therapy could be useful to individuals who have lost fertility as a result of cancer treatment (undergoing chemotherapy or radiation) as well as unrelated illnesses that prevent a woman from ovulating properly.
Note: Patients should consult gynaecologists to get advice about their situation and anticipated treatment outcome.
Why Apex Hospital in Sirsa Is Best for Infertility Treatments?
Thousands of women in Sirsa and other countries rely on Apex Hospital for fertility restoration. And there’s not one but multiple reasons behind that:
Experienced medical team: We boast a team of fertility experts, gynecologists, and stem cell therapy doctors who have 20+ years of cumulative experience and provide the best results in personalized treatment of patients.
Innovative technology: Our hospital boasts of the latest technologies in the treatment of medicine including ultrasound-guided stem cell infusion and up-to-date IVF laboratories. Offering precise and safe treatment!
Comprehensive fertility care: Apex provides integrated fertility services like hysteroscopy, laparoscopy, PRP therapy, and stem cell treatment – all under one roof. This leads to better treatment outcomes and patient convenience.
High success rates: With a track record of superior IVF and fertility treatment success rates (on par with international centers), Apex Hospital guarantees to provide tangible results and also become a hope for women with low AMH.
Patient-centered approach: We are also patient-centered. We focus on compassionate care, individualized treatment plans, and support of the patient at every step of their journey. You will feel informed and cared for all the way through.
Stem Cell Therapy for Low AMH: Final Words
There you go!
We told you everything important about undergoing stem cell therapy. Women struggling with low AMH or other fertility challenges now have a promising option. While still ongoing research, Dr. Manisha Metha believes it can turn out to be a groundbreaking advancement in fertility treatment. Offering renewed hope to many who thought their chances were limited.
With careful patient selection and continued scientific exploration, this therapy can actually redefine possibilities in reproductive health. Until then, let’s just sit back and hope for the best.
Got any queries to ask? Call us at +91 9168039000 and have them answered by our experts.
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